Description

(2-((4-Ethylpiperazin-1-yl)methyl)-5-fluorophenyl)boronic acid is a specialized boronic acid derivative featuring a fluorinated aromatic ring and an ethylpiperazine moiety. This compound is a critical high-purity building block in modern synthetic chemistry, valued for its role in forming stable carbon-boron bonds. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures central to drug discovery.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of complex molecules targeting neurological and oncological pathways.
• Ligand Synthesis: Used in the development of novel catalysts and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the creation of tools for studying enzyme function and protein interactions.
• Material Science Research: A building block for advanced polymers and organic electronic materials.
• Process Chemistry Development: Utilized in route scouting and optimization for scalable API manufacturing.

Basic Information

Item	Details
Product Name	(2-((4-Ethylpiperazin-1-yl)methyl)-5-fluorophenyl)boronic Acid
CAS No.	1312765-78-8
Molecular Formula	C13H20BFN2O2
Molecular Weight	266.12 g/mol
Synonyms	5-Fluoro-2-[(4-ethyl-1-piperazinyl)methyl]benzeneboronic Acid; (5-Fluoro-2-{[(4-ethylpiperazin-1-yl)methyl]})phenylboronic Acid; 2-[(4-Ethylpiperazin-1-yl)methyl]-5-fluorobenzeneboronic Acid; B-[2-[(4-Ethyl-1-piperazinyl)methyl]-5-fluorophenyl]boronic Acid; 1312765-78-8; Boronic acid, B-[2-[(4-ethyl-1-piperazinyl)methyl]-5-fluorophenyl]-
EINECS	Contact for details

Quality Control

Our (2-((4-Ethylpiperazin-1-yl)methyl)-5-fluorophenyl)boronic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.