Description

Abt-494 Enantiomer CAS NO 1310726-59-0 is a specific stereoisomer of a key pharmaceutical intermediate or reference standard. This high-purity enantiomer is critical for research and development in targeted drug discovery programs, particularly those focused on selective inhibition pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise chiral building blocks for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in API manufacturing.
• Drug Discovery & Medicinal Chemistry: Serves as a crucial chiral intermediate or building block in the synthesis of novel bioactive compounds and potential drug candidates.
• Biochemical Research: Employed in in vitro studies to investigate specific enzyme inhibition, receptor binding affinity, and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Acts as a starting material or intermediate for process optimization and pilot-scale synthesis of targeted molecules.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis, stereochemistry, and pharmacology.

Basic Information

Product Name	Abt-494 Enantiomer
CAS No.	1310726-59-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ABT-494 Enantiomer; (S)-ABT-494; Upadacitinib Enantiomer; JAK1 Inhibitor Enantiomer; (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide (enantiomer); ABT 494 Enantiomer; RINVOQ® (Upadacitinib) Related Enantiomer
EINECS	Contact for details

Quality Control

Our Abt-494 Enantiomer is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and stereochemical purity. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.