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2-Fluoro-6-Methylpyridin-4-Ylboronic Acid CAS NO 1310404-78-4


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CAS No.:1310404-78-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-6-Methylpyridin-4-Ylboronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its critical role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its ability to introduce the fluorinated pyridine moiety.
  • Material Science Research: Serves as a precursor for creating functional organic materials, including liquid crystals, organic light-emitting diodes (OLEDs), and conductive polymers.
  • Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems and protein interactions.
  • Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name 2-Fluoro-6-Methylpyridin-4-Ylboronic Acid
CAS No. 1310404-78-4
Molecular Formula C7H9BFNO2
Molecular Weight 168.96 g/mol
Synonyms (2-Fluoro-6-methylpyridin-4-yl)boronic acid; 2-Fluoro-6-methyl-4-pyridineboronic acid; 4-Borono-2-fluoro-6-methylpyridine; 2-Fluoro-6-methyl-4-pyridinylboronic acid; 2-Fluoro-6-methylpyridine-4-boronic acid; 2-Fluoro-6-methyl-4-pyridylboronic acid; 1310404-78-4
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Quality Control

Our 2-Fluoro-6-Methylpyridin-4-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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