Description

2,3-Difluoro-6-Chlorophenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoro-chloro substitution pattern confers specific biological activity.
• Material Science: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials requiring precise molecular architecture.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone reaction in medicinal and process chemistry.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compound libraries.
• Ligand and Catalyst Preparation: Used as a precursor for synthesizing specialized ligands and catalysts in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,3-Difluoro-6-Chlorophenylboronic Acid
CAS No.	1310404-70-6
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(2,3-Difluoro-6-chlorophenyl)boronic acid; 2-Chloro-3,4-difluorophenylboronic acid; 6-Chloro-2,3-difluorophenylboronic acid; B-(2,3-Difluoro-6-chlorophenyl)boronic acid; 2,3-Difluoro-6-chlorobenzeneboronic acid; (6-Chloro-2,3-difluorophenyl)boronic acid; CAS 1310404-70-6
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Chlorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.