Description

2-Trifluoroacetylpyridine-4-Boronic Acid CAS NO 1310404-58-0 is a high-value, multifunctional chemical building block that combines a pyridine core with both a trifluoroacetyl group and a boronic acid functionality. This unique structure makes it a critical intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid group enables efficient carbon-carbon bond formation, essential for creating complex biaryl and heterobiaryl structures in medicinal chemistry.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyridine-based ligands for transition metal catalysts used in asymmetric synthesis.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Utilized to develop labeled compounds and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Trifluoroacetylpyridine-4-Boronic Acid
CAS No.	1310404-58-0
Molecular Formula	C8H5BF3NO3
Molecular Weight	230.94 g/mol
Synonyms	4-Borono-2-(trifluoroacetyl)pyridine; 2-(Trifluoroacetyl)-4-pyridineboronic Acid; (2-(Trifluoroacetyl)pyridin-4-yl)boronic Acid; 4-Pyridineboronic acid, 2-(trifluoroacetyl)-; 2-Trifluoroacetyl-4-pyridinylboronic Acid; 4-Boron-2-trifluoroacetylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Trifluoroacetylpyridine-4-Boronic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.