Description

2-Fluoro-3-Hydroxy-6-Bromophenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring halogen and hydroxyl substituents, makes it a versatile intermediate for constructing complex molecules with precise spatial and electronic properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand for Catalysis: Employed in the development of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials and polymers.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars and other biological analytes.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-Fluoro-3-Hydroxy-6-Bromophenylboronic Acid
CAS No.	1309980-99-1
Molecular Formula	C6H5BBrFO3
Molecular Weight	234.82 g/mol
Synonyms	(2-Fluoro-3-hydroxy-6-bromophenyl)boronic acid; 6-Bromo-2-fluoro-3-hydroxybenzeneboronic acid; 2-Bromo-5-fluoro-6-hydroxybenzeneboronic acid; Boronic acid, B-(2-bromo-5-fluoro-6-hydroxyphenyl)-; 1309980-99-1; 2-Fluoro-3-hydroxy-6-bromobenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Hydroxy-6-Bromophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by techniques including HPLC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.