Description

2-Fluoro-3-Bromo-6-Ethoxyphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique halogenated and alkoxy-substituted aromatic structure makes it an indispensable reagent for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to create advanced herbicide and pesticide molecules with enhanced efficacy and selectivity.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology: Serves as a versatile handle for bioconjugation and the development of chemical probes and sensors.
• Academic & Process R&D: Utilized in methodological studies and scale-up process development for complex boronic acid chemistry.
• Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-3-Bromo-6-Ethoxyphenylboronic Acid
CAS No.	1309980-98-0
Molecular Formula	C8H9BBrFO3
Molecular Weight	262.87 g/mol
Synonyms	(2-Fluoro-3-bromo-6-ethoxyphenyl)boronic acid; 2-Fluoro-3-bromo-6-ethoxybenzeneboronic acid; 3-Bromo-2-fluoro-6-ethoxybenzeneboronic acid; Boronic acid, B-(2-fluoro-3-bromo-6-ethoxyphenyl)-; 1309980-98-0; 2-Fluoro-3-bromo-6-ethoxy phenylboronic acid; 2-Fluoro-3-bromo-6-ethoxybenzeneboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Bromo-6-Ethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.