Description

4-(Dimethylamino)-2,3,5-Trifluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique trifluoro-dimethylamino-substituted aromatic structure makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An essential reagent in medicinal chemistry for structure-activity relationship (SAR) studies and in process chemistry for route scouting and optimization.
• Fluorine Chemistry: A versatile substrate for further functionalization via cross-coupling, amidation, and esterification reactions, exploiting the reactivity of the carboxylic acid and the electron-donating dimethylamino group.

Basic Information

Product Name	4-(Dimethylamino)-2,3,5-Trifluorobenzoic Acid
CAS No.	1309602-70-7
Molecular Formula	C9H7F3NO2
Molecular Weight	218.15 g/mol
Synonyms	2,3,5-Trifluoro-4-(dimethylamino)benzoic Acid; 4-(N,N-Dimethylamino)-2,3,5-trifluorobenzoic Acid; Benzoic acid, 4-(dimethylamino)-2,3,5-trifluoro-; 4-Dimethylamino-2,3,5-trifluorobenzoic acid; 1309602-70-7; 4-(Dimethylamino)-2,3,5-trifluorobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-(Dimethylamino)-2,3,5-Trifluorobenzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against comprehensive specifications, including identity confirmation, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We operate under a cGMP-compliant quality management system suitable for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.