Description

C18:1 3'-Sulfo Galactosylceramide (D18:1/18:1(9Z)) is a high-purity, synthetic sulfatide, a critical class of bioactive sphingolipids. This compound, with CAS number 1292769-40-4, is essential for research into lipid metabolism, cellular signaling, and membrane biology. It is primarily utilized by biopharmaceutical researchers, diagnostic developers, and academic institutions focused on neurology, immunology, and metabolic disease studies.

Application

• Biomedical Research: Used as a standard or probe in studies of sulfatide biology, including their role in myelin function, neural development, and autoimmune disorders like multiple sclerosis.
• Drug Discovery & Screening: Serves as a target or substrate in high-throughput assays to identify modulators of enzymes like arylsulfatase A or galactosylceramide sulfotransferase for therapeutic development.
• Diagnostic Development: Employed in the development and calibration of diagnostic kits for measuring sulfatide levels, which can be biomarkers for certain lysosomal storage diseases (e.g., metachromatic leukodystrophy).
• Lipidomics & Analytical Standards: Acts as a critical reference standard for mass spectrometry (LC-MS/MS) and chromatography (HPLC) in lipidomic profiling to ensure accurate identification and quantification.
• Cell Biology Studies: Incorporated into lipid bilayers or liposomes to investigate membrane structure, lipid raft formation, and protein-lipid interactions in cellular models.
• Biochemical Reagent: Used as a substrate for in vitro enzymatic assays to study sulfatase or sulfotransferase activity and kinetics.

Basic Information

Product Name	C18:1 3'-Sulfo Galactosylceramide (D18:1/18:1(9Z))
CAS No.	1292769-40-4
Molecular Formula	C46H87NO11S
Molecular Weight	862.25 g/mol
Synonyms	Sulfogalactosylceramide (18:1/18:1); 3-O-Sulfo-β-D-galactosylceramide (D18:1/18:1(9Z)); (2S,3R,4E)-2-N-[(9Z)-Octadecenoyl]-1-(β-D-galactopyranosyl-3-sulfate)-4-octadecene-1,3-diol; Cerebroside Sulfate (18:1); Galactocerebroside Sulfate; Sulfatide (C18:1); SM4s; O3S-β-D-Galactosylceramide
EINECS	Contact for details

Quality Control

Our C18:1 3'-Sulfo Galactosylceramide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous analytical standards, utilizing techniques such as NMR, HPLC, and mass spectrometry for characterization.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.