Description

(5-Fluoro-2-(Morpholinomethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a reactive boronic acid group with a morpholine moiety, making it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for carbon-carbon bond formation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its structural features for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Acts as a versatile handle in the development of enzyme inhibitors, molecular probes, and bioconjugation reagents.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via high-throughput parallel synthesis for hit identification and lead optimization.
• Ligand Development: Serves as a starting material for synthesizing novel ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(5-Fluoro-2-(Morpholinomethyl)Phenyl)Boronic Acid
CAS No.	1292755-44-2
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	5-Fluoro-2-(morpholin-4-ylmethyl)phenylboronic acid; (5-Fluoro-2-((morpholin-4-yl)methyl)phenyl)boronic acid; 2-(Morpholinomethyl)-5-fluorophenylboronic acid; Boronic acid, B-[5-fluoro-2-[(4-morpholinyl)methyl]phenyl]-; 1292755-44-2; 5-Fluoro-2-morpholinomethylphenylboronic acid; [5-Fluoro-2-(morpholin-4-ylmethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-(Morpholinomethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.