Description

3-Fluoro-5-Formylbenzoic Acid is a versatile aromatic building block featuring both a carboxylic acid and an aldehyde functional group on a fluorinated benzene ring. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and aldehyde group contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and material science.
• Polymer and Material Science: Employed in the production of specialty polymers, liquid crystals, and organic electronic materials due to its ability to introduce both rigidity and specific polarity.
• Fluorescent Probe and Dye Synthesis: The formyl group is instrumental in constructing conjugated systems for imaging agents, sensors, and organic dyes.
• Cross-Coupling Reactions: The aromatic bromide/iodide derivative (readily prepared from this compound) is a valuable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	3-Fluoro-5-Formylbenzoic Acid
CAS No.	1289005-85-1
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	5-Formyl-3-fluorobenzoic Acid; 3-Fluoro-5-carboxybenzaldehyde; Benzoic acid, 3-fluoro-5-formyl-; 3-Fluoro-5-aldehydobenzoic Acid; 3-Fluoro-5-oxidanylidenemethyl-benzoic acid; 5-Carboxy-3-fluorobenzaldehyde; 3-Fluoro-5-formyl-benzoic acid; 3-Fluoro-5-formylbenzoic acid CAS 1289005-85-1
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Formylbenzoic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.