Description

Arachidonic Acid-D11 is a deuterium-labeled analog of the essential polyunsaturated fatty acid, arachidonic acid. This stable isotope-labeled compound is critical for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily utilized by researchers and analytical laboratories in the fields of lipidomics, metabolomics, and pharmaceutical development for precise measurement of arachidonic acid and its metabolites.

Application

• Quantitative Mass Spectrometry Internal Standard: Serves as a critical reference compound for the accurate quantification of endogenous arachidonic acid levels in biological samples (e.g., plasma, serum, tissue homogenates).
• Lipidomics and Metabolomics Research: Enables precise tracking and measurement of arachidonic acid metabolism, eicosanoid pathways, and lipid signaling in disease models and clinical studies.
• Pharmacokinetic and Drug Metabolism Studies: Used to study the bioavailability, distribution, and metabolism of drugs that interact with arachidonic acid pathways.
• Biochemical Assay Development: Acts as a calibrant or spike-in control for developing and validating high-sensitivity LC-MS/MS and GC-MS methods.
• Nutritional and Clinical Research: Facilitates investigations into the role of dietary fatty acids, inflammation, and related disorders by providing a reliable isotopic tracer.

Basic Information

Product Name	Arachidonic Acid-D11
CAS No.	1287387-84-1
Molecular Formula	C₂₀H₂₁D₁₁O₂
Molecular Weight	315.52 g/mol (approx.)
Synonyms	(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic-5,6,8,9,11,12,14,15,17,18,18-d11 acid; Arachidonic Acid-d11; All-cis-5,8,11,14-Eicosatetraenoic Acid-d11; AA-d11; 20:4(ω-6)-d11; Deuterated Arachidonic Acid; [D11]-Arachidonic Acid
EINECS	Contact for details

Quality Control

Our Arachidonic Acid-D11 is produced and tested to meet the exacting standards required for analytical and research applications. Each batch is characterized using advanced techniques including NMR and mass spectrometry to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for isotopic purity, chemical purity, and solvent content. Our quality management system ensures traceability and consistency for reliable research outcomes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen), as the compound is easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (NMR)	Conforms to structure
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 95%
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.