Description

3-(4-Fluorophenyl)-1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of molecular probes and tool compounds for target validation and drug discovery.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	3-(4-Fluorophenyl)-1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1286230-78-1
Molecular Formula	C16H20BFN2O2
Molecular Weight	302.15 g/mol
Synonyms	1-Methyl-3-(4-fluorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(4-fluorophenyl)-1-methyl-1H-pyrazole; 3-(4-Fluorophenyl)-1-methyl-1H-pyrazole-4-boronic acid pinacol ester; 1-Methyl-3-(p-fluorophenyl)-4-(pinacolatoboryl)pyrazole; 1286230-78-1; Pyrazole boronic ester derivative
EINECS	Contact for details

Quality Control

Every batch of our 3-(4-Fluorophenyl)-1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance in cGMP and ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.