Description

(S)-tert-Butyl 1-(Cyclopentanecarbonyl)Pyrrolidin-3-Ylcarbamate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its core value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and other therapeutic areas. This compound is essential for research institutions and pharmaceutical manufacturers engaged in process development and the production of complex, stereochemically defined drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug molecules, particularly for neurological and psychiatric disorders.
• API Development: Serves as a key precursor in the research and process development of new Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Utilized in medicinal chemistry for constructing stereocenters with high enantiomeric purity, crucial for drug efficacy and safety profiles.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to commercial manufacturing under cGMP conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and research organizations specializing in custom synthesis and early-stage drug development.
• Chemical Biology Research: Used as a scaffold or probe in studying biological pathways and protein-ligand interactions.

Basic Information

Item	Details
Product Name	(S)-tert-Butyl 1-(Cyclopentanecarbonyl)Pyrrolidin-3-Ylcarbamate
CAS No.	1286208-41-0
Molecular Formula	C15H26N2O3
Molecular Weight	282.38 g/mol
Synonyms	(S)-tert-Butyl (1-(cyclopentanecarbonyl)pyrrolidin-3-yl)carbamate; tert-Butyl N-[(3S)-1-(cyclopentanecarbonyl)pyrrolidin-3-yl]carbamate; (S)-1-Boc-3-amino-N-cyclopentylpyrrolidine; (S)-3-((tert-Butoxycarbonyl)amino)-1-(cyclopentanecarbonyl)pyrrolidine; (S)-1-Cyclopentanecarbonyl-3-(Boc-amino)pyrrolidine; (S)-N-Boc-3-amino-1-cyclopentanecarbonylpyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(Cyclopentanecarbonyl)Pyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for pharmaceutical R&D. Products undergo rigorous analytical testing, including HPLC, chiral HPLC, and 1H/13C NMR, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development under cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen) in a desiccated environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.