Description

4-(2-Methoxyethoxy)-3-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional benzoic acid derivative characterized by its trifluoromethyl and methoxyethoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis, enabling the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used as a precursor for developing new-generation herbicides and fungicides, where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and polar side chains.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like solubility, thermal stability, and adhesion for specialty coatings and resins.
• Organic Synthesis Reagent: Acts as a carboxylic acid component in coupling reactions (e.g., amide formation, esterification) for constructing complex molecular architectures in medicinal chemistry.
• Research & Development: Utilized in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in fluorine chemistry.

Basic Information

Product Name	4-(2-Methoxyethoxy)-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1271093-46-9
Molecular Formula	C11H11F3O4
Molecular Weight	264.20 g/mol
Synonyms	3-(Trifluoromethyl)-4-(2-methoxyethoxy)benzoic acid; 4-(2-Methoxyethoxy)-3-(trifluoromethyl)benzoic acid; Benzoic acid, 4-(2-methoxyethoxy)-3-(trifluoromethyl)-; 1271093-46-9; 4-(2-Methoxyethoxy)-α,α,α-trifluoro-m-toluic acid; 3-Trifluoromethyl-4-(2-methoxyethoxy)benzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Methoxyethoxy)-3-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.