Description

(S)-2-Methoxy-2-Phenylacetic acid is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its primary value lies in its utility for the preparation of enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and specialty chemical industries seeking to control stereochemistry in their synthetic routes.

Application

• As a chiral resolving agent for the separation of racemic mixtures of amines and other basic compounds.
• A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Used in the preparation of chiral ligands and catalysts for asymmetric catalysis.
• Employed as a building block for the synthesis of complex natural products and fine chemicals with defined stereochemistry.
• Utilized in analytical chemistry as a chiral derivatizing agent for HPLC and GC analysis to determine enantiomeric purity.
• Applied in agrochemical research for the development of enantiomerically pure herbicides and pesticides.

Basic Information

Product Name	(S)-2-Methoxy-2-Phenylacetic acid
CAS No.	1265228-47-4
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(S)-(-)-Mandelic acid methyl ether; (S)-O-Methylmandelic acid; (S)-α-Methoxyphenylacetic acid; L-(-)-Methoxy(phenyl)acetic acid; (2S)-2-Methoxy-2-phenylacetic acid; (S)-MPA; (S)-Methoxy(phenyl)acetic acid
EINECS	Contact for details

Quality Control

Our (S)-2-Methoxy-2-Phenylacetic acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.