Description

5-Methoxy-2,3,4-Trifluorobenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive acyl chloride group with methoxy and trifluoro substituents, enabling precise molecular modifications for enhanced properties. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Liquid Crystal Material Production: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorinated aromatic units into polymers, enhancing chemical resistance and thermal stability.
• Organic Synthesis Reagent: Acts as a versatile acylating agent for introducing the 5-methoxy-2,3,4-trifluorobenzoyl moiety into target molecules in research and fine chemical production.

Basic Information

Product Name	5-Methoxy-2,3,4-Trifluorobenzoyl Chloride
CAS No.	1263376-71-1
Molecular Formula	C8H4ClF3O2
Molecular Weight	232.56 g/mol
Synonyms	2,3,4-Trifluoro-5-methoxybenzoyl chloride; 5-Methoxy-2,3,4-trifluorobenzoic acid chloride; 2,3,4-Trifluoro-5-methoxybenzoic acid chloride; 5-Methoxy-2,3,4-trifluorobenzoylchloride; Benzoyl chloride, 5-methoxy-2,3,4-trifluoro-; 5-Methoxy-2,3,4-trifluoro benzoyl chloride
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2,3,4-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.