Description

2-Fluoro-5-(Thiophen-3-Yl)Benzoic Acid is a high-value fluorinated aromatic building block that combines a benzoic acid core with thiophene and fluorine substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure enables precise tuning of electronic and steric properties. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and organic electronics industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the bioactivity of the thiophene moiety.
• Organic Semiconductor Precursor: Serves as a building block for π-conjugated systems in organic light-emitting diodes (OLEDs) and field-effect transistors (OFETs).
• Ligand and Catalyst Development: The carboxylic acid group allows for functionalization into chelating ligands for transition metal catalysis.
• Material Science Research: Employed in the synthesis of novel polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Used to create fluorescent tags or molecular probes for studying biological processes.

Basic Information

Product Name	2-Fluoro-5-(Thiophen-3-Yl)Benzoic Acid
CAS No.	1261993-00-3
Molecular Formula	C11H7FO2S
Molecular Weight	222.24 g/mol
Synonyms	5-(3-Thienyl)-2-fluorobenzoic Acid; 2-Fluoro-5-(3-thienyl)benzoic Acid; Benzoic acid, 2-fluoro-5-(3-thienyl)-; 2-Fluoro-5-(thiophen-3-yl)benzoic acid; 3-(2-Fluoro-5-carboxyphenyl)thiophene; 2-Fluoro-5-(3-thiophenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Thiophen-3-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The container should be kept tightly sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.