Description

3'-(Benzyloxy)-3-Fluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity, fluorinated biphenyl carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which combines a fluorine atom and a benzyl-protected hydroxyl group on a biphenyl scaffold, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for targets requiring fluorinated biphenyl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Useful as a probe or linker molecule in bioconjugation and the study of biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3'-(Benzyloxy)-3-Fluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261981-29-6
Molecular Formula	C20H15FO3
Molecular Weight	322.33 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3'- (benzyloxy)-3-fluoro-; 3-Fluoro-3'-(benzyloxy)biphenyl-4-carboxylic acid; 3'-Benzyloxy-3-fluorobiphenyl-4-carboxylic acid; 4-Carboxy-3'-benzyloxy-3-fluorobiphenyl; 3-Fluoro-3'-benzyloxy-4-biphenylcarboxylic acid; 1261981-29-6; 3'-(Benzyloxy)-3-fluoro-1,1'-biphenyl-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3'-(Benzyloxy)-3-Fluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.