Description

3',5-Difluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid is a high-purity biphenyl dicarboxylic acid derivative distinguished by its strategically positioned fluorine atoms, which are critical for modulating electronic and steric properties in advanced molecular architectures. This compound serves as a versatile and valuable building block in pharmaceutical and agrochemical research, enabling the synthesis of complex active ingredients with enhanced biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and material science sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the difluorobiphenyl core contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a backbone for constructing sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Biology Probes: Utilized as a core scaffold for developing fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	3',5-Difluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid
CAS No.	1261978-52-2
Molecular Formula	C14H8F2O4
Molecular Weight	278.21 g/mol
Synonyms	3,4'-Biphenyldicarboxylic acid, 3',5-difluoro-; 3',5-Difluorobiphenyl-3,4'-dicarboxylic Acid; 3-(3,5-Difluorophenyl)-4-carboxybenzoic Acid; 4'-Carboxy-3',5-difluoro[1,1'-biphenyl]-3-carboxylic Acid; [1,1'-Biphenyl]-3,4'-dicarboxylic acid, 3',5-difluoro-; Difluorobiphenyl Dicarboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3',5-Difluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.