Description

5-(4-Cyanophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its molecular structure, featuring both a cyano and a fluorine substituent, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a core component in the synthesis of advanced organic electronic materials for displays and lighting applications.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal, optical, or mechanical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Coordination Chemistry Ligand: Potential use in the design of metal-organic frameworks (MOFs) and catalysts due to its carboxylic acid functionality.

Basic Information

Product Name	5-(4-Cyanophenyl)-2-Fluorobenzoic Acid
CAS No.	1261977-82-5
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	2-Fluoro-5-(4-cyanophenyl)benzoic Acid; 5-(4-Cyanophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-4-carbonitrile, 2'-fluoro-4'-carboxy-; 2'-Fluoro-4'-carboxy[1,1'-biphenyl]-4-carbonitrile; 4-(2-Fluoro-4-carboxyphenyl)benzonitrile; 2-Fluoro-4'-(4-cyanophenyl)benzoic Acid; Benzoic acid, 5-(4-cyanophenyl)-2-fluoro-
EINECS	Contact for details

Quality Control

Our 5-(4-Cyanophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.