Description

2-Fluoro-4-(2-Hydroxyphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique bifunctional structure, featuring both a phenolic hydroxyl and a carboxylic acid group on a fluorinated biphenyl core, makes it an exceptionally versatile building block for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where its fluorine atom and functional handles are leveraged to fine-tune biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like kinase inhibitors, anti-inflammatory agents, and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated chelating ligands for catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to specialized R&D projects.
• Academic & Industrial Research: Utilized in exploratory chemistry to study structure-activity relationships (SAR) and develop new synthetic methodologies involving fluorinated arenes.

Basic Information

Product Name	2-Fluoro-4-(2-Hydroxyphenyl)Benzoic Acid
CAS No.	1261975-31-8
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	2'-Hydroxy-[1,1'-biphenyl]-4-carboxylic acid, 2'-fluoro-; 2-Fluoro-4-(2-hydroxyphenyl)benzoic acid; [1,1'-Biphenyl]-4-carboxylic acid, 2'-fluoro-2-hydroxy-; 2'-Fluoro-2-hydroxy[1,1'-biphenyl]-4-carboxylic acid; 4-(2-Hydroxyphenyl)-2-fluorobenzoic Acid; 2-Fluoro-4-(o-hydroxyphenyl)benzoic Acid; Biphenyl-4-carboxylic acid, 2'-fluoro-2-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(2-Hydroxyphenyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for R&D and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this light-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.