Description

3'-Fluoro-4'-Methyl-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid CAS NO 1261972-04-6 is a high-value, multi-functional biphenyl carboxylic acid derivative featuring strategically positioned fluorine and trifluoromethyl groups. This compound is engineered to serve as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing monomers and polymers used in electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for more complex fluorinated aromatic systems in academic and industrial research.
• Material Science Research: Investigated for the development of novel polymers, coatings, and specialty chemicals with unique surface properties and resistance.

Basic Information

Product Name	3'-Fluoro-4'-Methyl-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1261972-04-6
Molecular Formula	C15H10F4O2
Molecular Weight	298.24 g/mol
Synonyms	[1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-4'-methyl-5-(trifluoromethyl)-; 3'-Fluoro-4'-methyl-5-(trifluoromethyl)biphenyl-3-carboxylic acid; 5-(Trifluoromethyl)-3'-fluoro-4'-methylbiphenyl-3-carboxylic acid; 3-Carboxy-3'-fluoro-4'-methyl-5-trifluoromethylbiphenyl; 1261972-04-6
EINECS	Contact for details

Quality Control

We maintain a strict quality management system aligned with cGMP principles for advanced intermediates. Every batch of 3'-Fluoro-4'-Methyl-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid is subjected to rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.