Description

2-Fluoro-4-(4-Formylphenyl)Benzoic Acid is a high-value aromatic building block containing both a carboxylic acid and a formyl functional group, enabling versatile downstream chemical modifications. This compound is critical for the synthesis of advanced pharmaceutical intermediates and functional organic materials, where its specific fluorine substitution pattern is essential for modulating biological activity and material properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Liquid Crystal & OLED Material Synthesis: Serves as a core building block for creating fluorinated aromatic monomers used in advanced display and lighting technologies.
• Agrochemical Active Ingredient Development: Used in research to develop novel herbicides and fungicides, where the fluorine atom enhances bioavailability and stability.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific thermal, optical, or chemical resistance properties to high-performance engineering plastics.
• Cross-coupling Reactions: The formyl and carboxylic acid groups make it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: Employed as a standard or reference compound in methodological studies and for exploring new synthetic pathways in academic and industrial labs.

Basic Information

Product Name	2-Fluoro-4-(4-Formylphenyl)Benzoic Acid
CAS No.	1261970-90-4
Molecular Formula	C14H9FO3
Molecular Weight	244.22 g/mol
Synonyms	4'-(Carboxy-3-fluorophenyl)-[1,1'-biphenyl]-4-carboxaldehyde; 4'-Formyl-[1,1'-biphenyl]-4-carboxylic Acid, 2-Fluoro Derivative; 2-Fluoro-4-(4-carboxyphenyl)benzaldehyde; [1,1'-Biphenyl]-4-carboxylic acid, 4'-formyl-2-fluoro-; 2-Fluoro-4'-formyl-[1,1'-biphenyl]-4-carboxylic Acid; 4-(4-Formylphenyl)-2-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-Formylphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.