Description

3-(3-Fluoro-2-Methylphenyl)-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the precise molecular architecture that combines a fluorinated methylphenyl group with a nitro-substituted benzoic acid, enabling targeted modifications in complex molecule synthesis. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is utilized to construct novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine and nitro functional groups for bioactivity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its rigid, substituted aromatic core.
• Organic Synthesis & Catalysis: Acts as a versatile substrate in cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination, for creating complex biaryl structures.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in manufacturing.

Basic Information

Product Name	3-(3-Fluoro-2-Methylphenyl)-5-Nitrobenzoic Acid
CAS No.	1261962-57-5
Molecular Formula	C15H10FNO4
Molecular Weight	287.24 g/mol
Synonyms	5-Nitro-3-(3-fluoro-2-methylphenyl)benzoic Acid; Benzoic acid, 3-(3-fluoro-2-methylphenyl)-5-nitro-; 3-(3-Fluoro-2-methylphenyl)-5-nitrobenzoic acid; 1261962-57-5; 3-(3-Fluoro-o-tolyl)-5-nitrobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-(3-Fluoro-2-Methylphenyl)-5-Nitrobenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets exacting R&D and scale-up requirements. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, guaranteeing traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.