Description

3-(4-Formylphenyl)-5-Trifluoromethylbenzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its formyl and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile organic synthesis building block for constructing complex molecular architectures. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes due to its reactive aldehyde functionality.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	3-(4-Formylphenyl)-5-Trifluoromethylbenzoic Acid
CAS No.	1261960-97-7
Molecular Formula	C15H9F3O3
Molecular Weight	294.23 g/mol
Synonyms	5-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid, 4'-formyl-; 4'-(Formyl)-5-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic Acid; 3-(4-Formylphenyl)-5-(trifluoromethyl)benzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-formyl-5-(trifluoromethyl)-; 4-Formylphenyl-5-trifluoromethylbenzoic Acid; 5-Trifluoromethyl-3-(4-formylphenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Formylphenyl)-5-Trifluoromethylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates, including those under cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizers, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.