Description

2-(4-Chlorophenyl)-6-Fluorobenzoic Acid is a high-purity fluorinated biphenyl carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines halogenated aromatic rings to enable precise structural modifications in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorinated biphenyl core contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its conjugated aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-(4-Chlorophenyl)-6-Fluorobenzoic Acid
CAS No.	1261921-07-6
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	6-Fluoro-2-(4-chlorophenyl)benzoic Acid; 2-(p-Chlorophenyl)-6-fluorobenzoic Acid; 4'-Chloro-2'-fluorobiphenyl-2-carboxylic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 4-chloro-2'-fluoro-; 2'-Fluoro-4-chlorobiphenyl-2-carboxylic Acid; 2-(4-Chlorophenyl)-6-fluorobenzoic Acid CAS 1261921-07-6
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-6-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure proper containment to avoid contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.