Description

3'-Fluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid is a high-purity biphenyl dicarboxylic acid derivative distinguished by its strategically placed fluorine substituent. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the introduction of both carboxylic acid functionality and fluorine atoms into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the synthesis of high-performance polyamides, polyesters, and liquid crystal polymers.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes due to its derivatizable carboxylic acid groups.

Basic Information

Item	Detail
Product Name	3'-Fluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid
CAS No.	1261915-32-5
Molecular Formula	C14H9FO4
Molecular Weight	260.22 g/mol
Synonyms	3,4'-Biphenyldicarboxylic acid, 3'-fluoro-; 3'-Fluoro-3,4'-biphenyldicarboxylic acid; 3-(3-Fluorophenyl)phthalic acid; 3-Fluoro-3',4'-dicarboxybiphenyl; [1,1'-Biphenyl]-3,4'-dicarboxylic acid, 3'-fluoro-; 3'-Fluorobiphenyl-3,4'-dicarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3'-Fluoro-[1,1'-Biphenyl]-3,4'-Dicarboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.