Description

2-Fluoro-5-(3-Methoxycarbonylphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its molecular structure, featuring both a benzoic acid and a methoxycarbonylphenyl moiety, makes it essential for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic electronic materials.
• Agrochemical Development: Intermediate in creating new-generation herbicides and fungicides with enhanced efficacy.
• Fluorine Chemistry Studies: A valuable substrate for investigating fluorination effects and structure-activity relationships (SAR) in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	2-Fluoro-5-(3-Methoxycarbonylphenyl)Benzoic Acid
CAS No.	1261912-57-5
Molecular Formula	C15H11FO4
Molecular Weight	274.24 g/mol
Synonyms	5-(3-Methoxycarbonylphenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 2'-fluoro-3'-methoxy-; 2-Fluoro-5-(3-methoxycarbonylphenyl)benzoic acid; 2'-Fluoro-3'-methoxy[1,1'-biphenyl]-3-carboxylic acid; 3-(2-Fluoro-5-carboxyphenyl)benzoic acid methyl ester; Methyl 3-(2-fluoro-5-carboxyphenyl)benzoate (tautomer); 2-Fluoro-5-(3-(methoxycarbonyl)phenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-(3-Methoxycarbonylphenyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.