Description

3-(3-Fluoro-4-Methylphenyl)-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of a nitro group and a fluorinated methylphenyl moiety, enabling precise molecular modifications and the construction of complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of new drug candidates, especially in developing molecules with potential anti-inflammatory, antimicrobial, or CNS activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and nitro groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, substituted aromatic structure.
• Chemical Biology & Proteomics: Employed as a derivatization agent or a scaffold for creating molecular probes and enzyme inhibitors.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	3-(3-Fluoro-4-Methylphenyl)-5-Nitrobenzoic Acid
CAS No.	1261903-43-8
Molecular Formula	C14H10FNO4
Molecular Weight	275.23 g/mol
Synonyms	5-Nitro-3-(3-fluoro-4-methylphenyl)benzoic Acid; 3-(3-Fluoro-4-methylphenyl)-5-nitrobenzoic acid; Benzoic acid, 3-(3-fluoro-4-methylphenyl)-5-nitro-; 1261903-43-8; 3-(3-Fluoro-p-tolyl)-5-nitrobenzoic acid; 3-(3-Fluoro-4-methyl-phenyl)-5-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-4-Methylphenyl)-5-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.