Description

2,3'-Difluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its precise molecular architecture, which is engineered to introduce specific steric and electronic properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro and methyl substituents modulate biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing thermal stability and electronic properties.
• Polymer & Material Science: Acts as a monomer or functional additive for creating specialty polymers with enhanced chemical resistance, low surface energy, or specific optical characteristics.
• Chemical Research & Development: A versatile scaffold in academic and industrial R&D for exploring new reactions, catalysis, and the development of functional organic compounds.

Basic Information

Product Name	2,3'-Difluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261893-04-2
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	4'-Methyl-2,3'-difluorobiphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 2,3'-difluoro-4'-methyl-; 2,3'-Difluoro-4'-methylbiphenyl-4-carboxylic acid; 2,3'-Difluoro-4'-methyl-1,1'-biphenyl-4-carboxylic acid; 4-Carboxy-2',3-difluoro-4-methylbiphenyl; Difluoromethylbiphenylcarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2,3'-Difluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.