Description

5-Chloro-2,4-Difluoro-Benzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Custom Synthesis: Provides a foundational structure for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Chloro-2,4-Difluoro-Benzoic Acid Methyl Ester
CAS No.	1261802-94-1
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	Methyl 5-Chloro-2,4-difluorobenzoate; Benzoic acid, 5-chloro-2,4-difluoro-, methyl ester; 2,4-Difluoro-5-chlorobenzoic acid methyl ester; 5-Chloro-2,4-difluorobenzoic acid methyl ester; Methyl 5-chloro-2,4-difluorobenzoate; 1261802-94-1
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Difluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.