Description

5-Iodo-2-(Trifluoromethyl)Phenylacetic Acid is a high-purity, multi-functional aromatic carboxylic acid building block, distinguished by its unique combination of iodine and trifluoromethyl substituents. This compound is engineered to provide exceptional reactivity and stability, making it a critical intermediate for synthesizing advanced molecules with tailored properties. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the iodine and trifluoromethyl groups.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in catalysis and as a building block for organometallic complexes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen functionality.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs serving the fine chemical industry.

Basic Information

Item	Details
Product Name	5-Iodo-2-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1261778-13-5
Molecular Formula	C9H6F3IO2
Molecular Weight	330.04 g/mol
Synonyms	2-(5-Iodo-2-(trifluoromethyl)phenyl)acetic acid; [5-Iodo-2-(trifluoromethyl)phenyl]acetic acid; α-(5-Iodo-2-trifluoromethylphenyl)acetic acid; 5-Iodo-2-trifluoromethylphenylacetic acid; 5-Iodo-α-methyl-2-(trifluoromethyl)benzenacetic acid; (5-Iodo-2-(trifluoromethyl)phenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Iodo-2-(Trifluoromethyl)Phenylacetic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.