Description

2-Fluoro-5-(2-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups can improve biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, or specific optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel fluorination chemistry, cross-coupling reactions, and as a scaffold for library synthesis in drug discovery.

Basic Information

Product Name	2-Fluoro-5-(2-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1261772-06-8
Molecular Formula	C14H8F4O2
Molecular Weight	292.21 g/mol
Synonyms	[2-Fluoro-5-(2-trifluoromethylphenyl)]benzoic acid; 2'-Fluoro-5'-(2-trifluoromethylphenyl)benzoic acid; 2-Fluoro-5-[2-(trifluoromethyl)phenyl]benzoic Acid; Benzoic acid, 2-fluoro-5-[2-(trifluoromethyl)phenyl]-; 1261772-06-8
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(2-Trifluoromethylphenyl)Benzoic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to ensure reliable performance and batch-to-batch consistency for your critical synthesis workflows. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.