Description

3-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid building block. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique trifluoromethyl and fluorine substituents impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1261750-12-2
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	3-Fluoro-4-[3-(trifluoromethyl)phenyl]benzoic Acid; 4-(3-(Trifluoromethyl)phenyl)-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-4-[3-(trifluoromethyl)phenyl]-; 1261750-12-2; 3-Fluoro-4-(3-trifluoromethylphenyl)benzoic acid; [3-Fluoro-4-(3-trifluoromethylphenyl)]benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.