Description

2,2',3'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-value fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluorinated structure offers enhanced metabolic stability and lipophilicity, making it indispensable for developing novel active compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating next-generation products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms contribute to improved bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronic Materials: Employed in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Advanced Material Science: Acts as a monomer or modifier for creating specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	2,2',3'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261625-13-1
Molecular Formula	C13H7F3O2
Molecular Weight	252.19 g/mol
Synonyms	2,2',3'-Trifluorobiphenyl-4-carboxylic Acid; 4-Carboxy-2,2',3'-trifluorobiphenyl; [1,1'-Biphenyl]-4-carboxylic acid, 2,2',3'-trifluoro-; 2,2',3'-Trifluoro-1,1'-biphenyl-4-carboxylic acid; 2,2',3'-Trifluoro-4-biphenylcarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,2',3'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.