Description

Ethyl 2-Hydroxy-5-(Trifluoromethyl)Benzoate is a high-value fluorinated benzoate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique combination of the phenolic hydroxyl and trifluoromethyl groups, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise building blocks for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas like anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine-containing side chains, improving polymer properties like chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new fluorination methodologies and structure-activity relationships (SAR).
• Fine Chemical Production: Intermediate in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific fluorinated aromatic structures.

Basic Information

Product Name	Ethyl 2-Hydroxy-5-(Trifluoromethyl)Benzoate
CAS No.	1261620-38-5
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	Ethyl 5-(Trifluoromethyl)salicylate; 2-Hydroxy-5-(trifluoromethyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-hydroxy-5-(trifluoromethyl)-, ethyl ester; Ethyl 2-hydroxy-5-trifluoromethylbenzoate; 5-(Trifluoromethyl)salicylic Acid Ethyl Ester; Ethyl 5-(Trifluoromethyl)-2-hydroxybenzoate; Ethyl α-hydroxy-5-(trifluoromethyl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Hydroxy-5-(Trifluoromethyl)Benzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.