Description

4-Chloro-2-(Trifluoromethoxy)Benzoic Acid, 97% is a high-purity, multi-functional aromatic carboxylic acid derivative, distinguished by its unique combination of chloro and trifluoromethoxy substituents. This compound is a critical advanced pharmaceutical intermediate and agrochemical building block, valued for its ability to impart metabolic stability and lipophilicity to target molecules. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials for displays and organic light-emitting diodes due to its aromatic core and halogenated properties.
• Polymer Modification: Acts as a monomer or cross-linking agent for engineering plastics and high-performance polymers requiring specific chemical resistance and thermal stability.
• Organic Synthesis & Catalysis: Employed as a versatile building block in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in organometallic catalysis.
• Chemical Research (R&D): A valuable reagent for medicinal chemistry and material science research programs exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-Chloro-2-(Trifluoromethoxy)Benzoic Acid, 97%
CAS No.	1261605-70-2
Molecular Formula	C8H4ClF3O3
Molecular Weight	240.56 g/mol
Synonyms	4-Chloro-2-(trifluoromethoxy)benzoic acid; 2-Trifluoromethoxy-4-chlorobenzoic acid; Benzoic acid, 4-chloro-2-(trifluoromethoxy)-; 4-Chloro-α,α,α-trifluoro-o-anisic acid; 4-Chloro-2-(trifluoromethoxy)benzenecarboxylic acid; 1261605-70-2; 4-Chloro-2-trifluoromethoxybenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethoxy)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the specified 97% purity and impurity profile. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent levels is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.