Description

4-Fluoro-3-(3-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to create novel active ingredients with improved efficacy and patent life.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes, enzyme inhibitors, and labeled compounds for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-(3-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1261593-39-8
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	4-Fluoro-3-[3-(trifluoromethyl)phenyl]benzoic acid; 3'-Trifluoromethyl-4-fluorobiphenyl-3-carboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-3'-(trifluoromethyl)-; 4-Fluoro-3'-(trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid; 4-Fluoro-3-(3-trifluoromethyl-phenyl)-benzoic acid; 4-Fluoro-3-(α,α,α-trifluoro-m-tolyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(3-Trifluoromethylphenyl)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.