Description

Dehydroepiandrosterone-[D6] (Certimass Solution) is a high-purity, stable isotope-labeled internal standard, specifically designed for precise quantitative analysis in mass spectrometry. This compound is critical for ensuring analytical accuracy and reliability in research and quality control laboratories. It is an essential tool for scientists and technicians in pharmaceutical development, clinical research, and forensic toxicology who require uncompromised data integrity for method validation and compliance.

Application

• Quantitative Mass Spectrometry: Serves as an internal standard for the accurate LC-MS/MS quantification of endogenous Dehydroepiandrosterone (DHEA) and its metabolites in biological matrices.
• Clinical Research & Diagnostics: Enables precise measurement of steroid hormone levels in serum, plasma, and urine for studies on adrenal function, aging, and endocrine disorders.
• Pharmaceutical Bioanalysis: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and ensure compliance with FDA and EMA bioanalytical method validation guidelines.
• Doping Control & Forensic Toxicology: Provides definitive reference for the detection and confirmation of exogenous steroid administration in sports and forensic investigations.
• Endocrinology Research: Facilitates reliable research into steroidogenesis, hormone replacement therapies, and the role of DHEA in various physiological and pathological processes.
• Method Development & Validation: Critical for developing, optimizing, and validating robust analytical methods, correcting for matrix effects and instrument variability.

Basic Information

Product Name	Dehydroepiandrosterone-[D6] (Certimass Solution)
CAS No.	1261170-80-2
Molecular Formula	C19H22D6O2
Molecular Weight	294.45 g/mol
Synonyms	DHEA-d6; 3β-Hydroxy-5-androsten-17-one-d6; Androstenolone-d6; Dehydroisoandrosterone-d6; Prasterone-d6; 5-Androsten-3β-ol-17-one-d6; (3β)-3-Hydroxyandrost-5-en-17-one-d6; Certimass™ DHEA-d6 Solution
EINECS	Contact for details

Quality Control

Every batch of Dehydroepiandrosterone-[D6] (Certimass Solution) is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity through rigorous testing via NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific data on purity, concentration, solvent, and isotopic enrichment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at the recommended temperature as specified on the label or COA (typically 2-8°C or -20°C for long-term stability). Due to its volatile solvent nature, handle with appropriate ventilation. Keep the container tightly sealed when not in use to prevent evaporation and concentration change.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Enrichment	≥ 99.0% D6
Concentration	100 µg/mL (or as specified)
Solvent	Methanol, Acetonitrile, or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.