Description

3-Fluoro-4-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to create novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated moiety enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and light-emitting materials due to its electron-withdrawing properties.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Studies: Used as a model compound to study the effects of polyfluorinated alkoxy groups on chemical reactivity and physical properties.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1261148-97-3
Molecular Formula	C10H6F4O3
Molecular Weight	250.15 g/mol
Synonyms	(E)-3-[3-Fluoro-4-(trifluoromethoxy)phenyl]acrylic Acid; 3-Fluoro-4-(trifluoromethoxy)cinnamic acid; 2-Propenoic acid, 3-[3-fluoro-4-(trifluoromethoxy)phenyl]-, (2E)-; 3-Fluoro-4-trifluoromethoxycinnamic Acid; (E)-3-(3-Fluoro-4-(trifluoromethoxy)phenyl)acrylic Acid; 3-Fluoro-4-(trifluoromethoxy)benzeneacrylic acid; 4-Trifluoromethoxy-3-fluorocinnamic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(Trifluoromethoxy)Cinnamic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.