Description

Didemethyl Citalopram Hydrobromide is a key pharmaceutical intermediate and reference standard used in the research, development, and quality control of active pharmaceutical ingredients (APIs). This compound is of significant importance for ensuring the purity, efficacy, and safety of related therapeutic agents. It is primarily needed by pharmaceutical manufacturers, analytical laboratories, and research institutions focused on neuropharmacology and antidepressant development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced citalopram derivatives and related active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories.
• Metabolite Research: Serves as a standard for studying the metabolic pathways and pharmacokinetics of citalopram and escitalopram.
• Impurity Profiling: Essential for identifying and quantifying related substances and degradation products in drug substance and finished product analysis.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic routes and structure-activity relationships (SAR) of selective serotonin reuptake inhibitors (SSRIs).
• Regulatory Compliance: Supports regulatory filings and submissions by providing a characterized material for stability studies and specification setting.

Basic Information

Product Name	Didemethyl Citalopram Hydrobromide
CAS No.	1260887-85-1
Molecular Formula	C18H19FN2O • HBr
Molecular Weight	383.27 g/mol
Synonyms	1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Hydrobromide; Desmethylcitalopram Hydrobromide; Citalopram Impurity Hydrobromide; Citalopram N-Desmethyl Hydrobromide; Citalopram Related Compound HBr; Lu 10-131-A Hydrobromide; Didesmethylcitalopram HBr
EINECS	Contact for details

Quality Control

Our Didemethyl Citalopram Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.