Description

Methyl 2-Fluoro-3-Iodobenzoate is a high-purity, multi-functional halogenated aromatic ester building block. This compound is critical for advanced organic synthesis, offering precise reactivity for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as cross-coupling reactions and fluorinated intermediate synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with enhanced biological activity.
• Cross-Coupling Reactions: Serves as a versatile substrate for Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis.
• Fluorinated Material Precursor: A starting material for synthesizing fluorinated liquid crystals, polymers, and electronic chemicals.
• Chemical Research & Development: Essential for method development and exploring new synthetic pathways in academic and industrial labs.

Basic Information

Product Name	Methyl 2-Fluoro-3-Iodobenzoate
CAS No.	1260830-14-5
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	2-Fluoro-3-iodobenzoic acid methyl ester; Methyl 2-fluoro-3-iodobenzoate; Benzoic acid, 2-fluoro-3-iodo-, methyl ester; 3-Iodo-2-fluorobenzoic acid methyl ester; Methyl 3-iodo-2-fluorobenzoate; 1260830-14-5; Methyl o-fluoro-m-iodobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.