Description

1-(2,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid is a high-purity, fluorinated carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical sector where its difluorophenyl and cyclopentane motifs are valuable. It is primarily needed by research chemists and process development teams in pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers and advanced materials with tailored properties.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	1-(2,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid
CAS No.	1260826-90-1
Molecular Formula	C12H12F2O2
Molecular Weight	226.22 g/mol
Synonyms	1-(2,5-Difluorophenyl)cyclopentanecarboxylic acid; 2,5-Difluoro-α,α-cyclopentylbenzenecetic acid; Cyclopentanecarboxylic acid, 1-(2,5-difluorophenyl)-; 1260826-90-1; 1-(2,5-Difluorophenyl)-1-cyclopentanecarboxylic Acid; α-Cyclopentyl-2,5-difluorobenzeneacetic acid
EINECS	Contact for details

Quality Control

Our 1-(2,5-Difluorophenyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.