Description

4-(3-Fluoropyridin-2-yl)benzoic acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a benzoic acid moiety linked to a fluorinated pyridine ring, makes it an invaluable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for synthesizing organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the development of chemical tools for biological study.

Basic Information

Product Name	4-(3-Fluoropyridin-2-yl)benzoic Acid
CAS No.	1260650-69-8
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-(4-Carboxyphenyl)-3-fluoropyridine; 3-Fluoro-2-(4-carboxyphenyl)pyridine; 4-(3-Fluoro-2-pyridinyl)benzoic Acid; Benzoic acid, 4-(3-fluoro-2-pyridinyl)-; 1260650-69-8; 4-(3-Fluoropyridin-2-yl)benzoic acid; 4-(3-Fluoro-2-pyridyl)benzoic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is accompanied by a comprehensive Certificate of Analysis (COA). Our standard purity specification for this product is ≥97% (by HPLC), with specifications for related substances and residual solvents available. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.