Description

2-Amino-4-(Trifluoromethoxy)Benzoic Acid is a high-value, multifunctional aromatic building block distinguished by its trifluoromethoxy and amino-carboxylic acid functional groups. This compound is critical for introducing specific steric and electronic properties into target molecules, enhancing their metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials requiring specific fluorine-containing motifs.
• Chemical Biology Probes: Useful for designing fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.

Basic Information

Product Name	2-Amino-4-(Trifluoromethoxy)Benzoic Acid
CAS No.	1259323-62-0
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	2-Amino-4-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-amino-4-(trifluoromethoxy)-; 4-(Trifluoromethoxy)anthranilic acid; 2-Amino-α,α,α-trifluoro-p-anisic acid; 2-Amino-4-trifluoromethoxybenzoic acid; 2-Amino-4-(trifluoromethoxy)benzoic acid CAS 1259323-62-0
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.