Description

[(2S,4R)-4-Amino-1-Methyl-2-Pyrrolidinyl]Methanol (Saltdata: Free) is a high-purity chiral pyrrolidine derivative, a crucial building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and catalysts in stereoselective synthesis.
• Agrochemical Research: Building block for developing advanced, enantiomerically pure pesticides and herbicides.
• Academic & R&D Laboratories: Serves as a standard or starting material for methodological studies in organic and medicinal chemistry.
• Peptidomimetics: Incorporated into peptide backbones to create conformationally restricted analogs with enhanced biological stability.
• Custom Synthesis: Foundation for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	[(2S,4R)-4-Amino-1-Methyl-2-Pyrrolidinyl]Methanol (Saltdata: Free)
CAS No.	1256636-31-3
Molecular Formula	C7H16N2O
Molecular Weight	144.22 g/mol
Synonyms	(2S,4R)-4-Amino-1-methyl-2-pyrrolidinemethanol; (2S,4R)-1-Methyl-4-amino-2-pyrrolidinemethanol; 4-Amino-1-methyl-2-pyrrolidinemethanol (stereoisomer); (2S,4R)-4-Amino-1-methylpyrrolidine-2-methanol; (4R)-4-Amino-1-methyl-L-prolinol; A chiral aminomethylpyrrolidine derivative
EINECS	Contact for details

Quality Control

Our [(2S,4R)-4-Amino-1-Methyl-2-Pyrrolidinyl]Methanol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical development. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.