Description

4-(2-Chloro-4-Fluorophenylmethoxy)Phenylboronic Acid is a specialized boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its ability to introduce complex aromatic systems.
• Material Science: Serves as a monomer or cross-linking agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile reagent for academic and industrial R&D labs for constructing complex organic molecules via Suzuki-Miyaura and other cross-coupling methodologies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial production of fine chemicals.

Basic Information

Product Name	4-(2-Chloro-4-Fluorophenylmethoxy)Phenylboronic Acid
CAS No.	1256355-86-8
Molecular Formula	C13H11BClFO3
Molecular Weight	279.49 g/mol
Synonyms	[4-[(2-Chloro-4-fluorophenyl)methoxy]phenyl]boronic acid; 2-Chloro-4-fluoro(4-boronatobenzyloxy)benzene; 4-[(2-Chloro-4-fluorobenzyl)oxy]benzeneboronic acid; 4-(2-Chloro-4-fluorobenzyloxy)phenylboronic acid; 4-(2-Chloro-4-fluorobenzyloxy)benzeneboronic acid; B-[4-[(2-Chloro-4-fluorophenyl)methoxy]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-4-Fluorophenylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.