Description

{2-[(3-Chlorophenyl)Methoxy]-5-Fluorophenyl}Boronic Acid is a high-purity, synthetically valuable organoboron compound. This chemical serves as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Employed in the creation of organic electronic materials, such as polymers for OLEDs and sensors, due to its functionalized aromatic structure.
• Chemical Synthesis: Acts as a versatile reagent in Suzuki-Miyaura cross-coupling reactions to construct biaryl and heterobiaryl structures prevalent in many advanced molecules.
• Ligand & Catalyst Development: Useful for modifying and creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	{2-[(3-Chlorophenyl)Methoxy]-5-Fluorophenyl}Boronic Acid
CAS No.	1256355-83-5
Molecular Formula	C13H11BClFO3
Molecular Weight	279.49 g/mol
Synonyms	(2-((3-Chlorophenoxy)methyl)-4-fluorophenyl)boronic acid; 2-[(3-Chlorophenoxy)methyl]-5-fluorobenzeneboronic acid; 5-Fluoro-2-[(3-chlorophenoxy)methyl]phenylboronic acid; [2-[(3-Chlorophenoxy)methyl]-5-fluorophenyl]boronic acid; Boronic acid, B-[2-[(3-chlorophenoxy)methyl]-5-fluorophenyl]-; CAS 1256355-83-5
EINECS	Contact for details

Quality Control

Our {2-[(3-Chlorophenyl)Methoxy]-5-Fluorophenyl}Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.