Description

2-(3-Fluorophenylmethoxy)-5-Methylphenylboronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures via cross-coupling reactions. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of the fluorinated biphenyl moiety.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and sensors.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical and CDMO companies producing bespoke compounds for client projects.

Basic Information

Product Name	2-(3-Fluorophenylmethoxy)-5-Methylphenylboronic Acid
CAS No.	1256355-82-4
Molecular Formula	C14H14BFO3
Molecular Weight	260.07 g/mol
Synonyms	5-Methyl-2-[(3-fluorobenzyl)oxy]benzeneboronic Acid; (5-Methyl-2-((3-fluorobenzyl)oxy)phenyl)boronic Acid; 2-[(3-Fluorobenzyl)oxy]-5-methylphenylboronic Acid; 2-(3-Fluorobenzyloxy)-5-methylphenylboronic Acid; B-[5-Methyl-2-[(3-fluorophenyl)methoxy]phenyl]boronic Acid; [5-Methyl-2-(3-fluorobenzyloxy)phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluorophenylmethoxy)-5-Methylphenylboronic Acid is manufactured under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical characterization including NMR, HPLC, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.